All three of your RB should do well this week. They are all struggling and their teams arent doing that well and havent given them the ball that much.
At WR I'd stay with Holt and start Chambers. K.C. has given up 326. 320 and 410 yards in their first 3 games. All number one recievers went off against the Chiefs....and in each game the Chiefs played, the #1 and #2 recievers had big days, for Cleveland (Q.Morgan and Johnson), Jacksonville (P.Johnson and J.Smith) and N.E. (T.Brown and Patten).