Will Holmes make it? Well, let's ask some other questions first.
Will LT survive the punishment of facing 8 man fronts constantly because his team can't throw?
Will Portis's bangs and bruises eventually wear him down and force him out early this season?
Will Faulk, George, or James return to their former status, or continue to be plagued from injuries previously sustained?
Will fear Jamal Lewis enough to have guys go after him to try and take him out of the game?
The point is, you can question the health of just about every major RB in the NFL because health is a fickle thing in football, especially at RB. Holmes has just as good a shot of surviving the season as any of these guys. So he's had hip surgery. His playing certainly doesn't show it. So he's approaching 30. Terrell Davis didn't even get 3 good seasons in the NFL, but Emmitt Smith is still running, so age isn't everything. The main point to me is that Holmes has shown in the past 2 years he can out-produce every other nfl RB, and he's continuing to do so this year. If I wanted to play it safe, I wouldn't have drafted him. He got drafted because he wins games, he makes the difference during tough matchups, and he wins championships for people. Onyl in a keeper league would I even consider trading him off.