I pick 1 DEF/ST. Use my other draft spots on sleepers/fliers. When the bye week comes up, I just drop/trade one of the sleepers/fliers for the fill-in DEF/ST. By that time, maybe a DEF that's on the WW might actually be pretty good enough to keep and play match-ups with.
ComeAtMeBro! - PPR
RB: Run DMC, SRidley, KMoreno, DMurray and BBrown
WR: RWhite, DThomas, and CGivins
TE: Hernandez and Gates
D/ST: Jets, DisChargers and 'Phins
Start QB, 2RB, 2WR, TE, Flex, K and D/ST