Couch should put up decent numbers this week. But remember that he hasn't really thrown for high yardage and multiple TDs yet this year. He'll stay consistent and pick apart the SD secondary using all 4 wrs. The loss of Faine and Ohara will hurt them, but they have some "competent" replacements to use in their absence.
IMO, the key to this game will be in Cleveland's defense. They've been able to hold off some top WRs (Harrison, Owens, Ward and Burress). They'll be able to fend off Boston this week, but LT2 could pose a problem for them. Look for Willie Green to get his hands on the ball plenty of times this week as well.