Generally what I've done is ranked the very best RBs (top 15 or so). Then I rank my top couple of QBs, throw in Gates, and rank my top5-7 WRs. Then throw in the top kicker or 2 and the top D or two.
Usually everyone else is heavy on the RBs first, then WRs, then QBs, and every one else comes later. By bucking this trend you should still end up with a couple of good to great back and receivers and still have the best shot at landing the top QB, TE, K, and D.
I tried this for the first time last season. Unbelievably I ended up with the No.1 pick. I dont know everyone I had, but I had LT, Manning, Colston (at TE), Ravens D, and Vinatieri. My other players were all solid (I think I had Parker and Wayne (?)) and I won the league fairly easily. (Of course I had to use the WW shrewdly also.)