Truthfully, from the list, it depends on which one you feel comfortable with and if you prefer rooting for a team.
Of the list, I like Pitt and JAC, but I don't see much of an advantage either way. DEF changes from yr to yr and its harder to predict than the rest of the positions. For example, I think CAR will have a great DEF this year (may be the colored glasses from being a fan) plus I root for the team, so I waited until the next to last pick to take them as my defense. So it's great as I can root for the game in fantasy and real life. And nobody even looks in that team's defense's direction for fantasy.
I would advise to take whoever you are comfortable with and watch the WW. Some defense will surprise and be worth a pickup.