Sitting 2-3 right now Here's my draft's notable picks:
3. Brady
22. Jacobs
27. Maroney

(Value probably ruined when Brady went down. It was a bit of a hedge against Brady in case NE went more balanced this year.)
46. Ronnie Brown
94. Chris Johnson
99. Bradshaw
118. DeSean Jackson
142. Jake Delhomme (Warner was still there, but buried in the yahoo ranks. Still miffed about that one, but Delhomme has been coming around.)
The first three weeks were a disaster for my team, though I did manage to win in week 1 in spite of the Brady injury.
I feel good for the future as my core is
RB: Jacobs, Ronnie, Chris Johnson
WR: Holmes, Bowe, Jackson
Now I'm feeling really good about my top 3 RBs and my WRs have no shortage of upside.
Also grabbed O'Sullivan. It's a competitive 12 team league with 6 playoff spots so I'm still right in the thick of it, but my team took a massive hit in week 1. I've moved on emotionally by now, but there's no glossing over the fact that the worst thing that could possibly happen to a fantasy team happened to my team and it shows. It'll never be as good as it could have been, but you never know in H2H Fantasy. It's all about getting hot at the right time. In fantasy basketball 2 years ago I lost 2 of my top 3 picks (Amare Stoudemire and Chris Bosh), but I didn't give up and punted the big men cats (REBs, Blocks FG%) to sweep the little men cats (Points, 3Pts, Assists, STLs, FT%) and I rode that strategy to a league title.
Fantasy is all about adjusting on the fly and constantly maintaining whatever edge you can, especially in H2H where you can't just amass a big lead (like in Roto baseball) and coast home. I'll be scraping for every point I can and hopefully I can turn the Brady injury into the most unlikely, and therefore that much more gratifying, of fantasy titles. Anything can happen.