people debate this a lot, and i think for the most part it's personal choice, but drafting at the 1-3 or 8-10 has always netted me better teams (or so it seems) than drafting in the middle.
you can effectively fill a position in one move when you're at the end, grabbing pairs of RBs and WRs, or you can start QB and TE runs since you can grab a skill position player with one pick and then a stud QB/TE with the other. you can often deal down from the 1-3 spot to the 8-10 and net yourself some bonus picks in the process. or, grab a certifiable stud rusher.
so i'd take 1-3 or 8-10 over 4-7. i'd personally be interested to hear from someone who likes the middle.
I usually prefer the front or back of the draft but this year I would prefer the middle. I have been going RB-WR-WR-RB-QB for the most part from this position and have been satisfied with the results. My first RB is usually whoever I am feeling that day. After AD, this years RB class has a lot of question marks. Even he is kind of questionable given his load last season. I have had good results landing two of Moss, Megatron, and Jennings in the 2nd and 3rd and PThomas as my 2nd RB in the 4th. I usually go with Rodgers in the 5th but sometimes I wait until later to get a couple mediocre QBs. Usually depends if I am able to land PThomas in the 4th or not.
But this is based on my own preferences for certain players so your mileage may vary.
"Maurice Jones-Drew, below the waist, is incredible." Mike Mayock
I personnally like the 3rd spot. You end up with a stud RB like Forte,MJD,Turner. 2nd round you snag a top receiver like Wayne, S.Smith, Jennings. Then I follow it up with Brees or Brady in the 3rd. 4th round talent like Lynch or McFadden is usually there at RB, while Edwards or Ochocinco sit there at WR, sometimes I even snag the top TE Witten if nothing peaks my interest.
So you get top RB, top QB, top TE, and top 8 WR. Just my prefence.
I think drafting at or near the end carries the inherent advantage of being able to know who will be there for the next pick. When you pick in the middle, you really don't have much of a clue who will still be there, or the list will be large. When you're within the third or third to last picks, you only have 2or 4 picks after the turn, which gives you a small possibility of who is there. You really don't have to worry "if I go WR here will the desirable RBs be dried up next pick, leaving me with little value?" etc. You can analyze the prior picks of 1 or 2 teams much better than if you're in the middle, and it's a crapshoot, and you can predict who they're going to pick at the turn. I prefer picking near the turn, but being on the turn takes away the advantage of knowing with almost certainty who will be there again, so you can choose your player/position accordingly.
I would imagine somebody who simply drafts on value won't care all that much what position they're at, and it would be more dependent on what the draft will look like in the first and second rounds.
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I think every year is different, depending on where you have the first dropoff in talent. I think this year AP, Forte, MJD, and Turner are the upper tier but without alot of seperation between them so i'd go for pick 4 to get an earlier 2nd round pick.
i usually dont like the bookend picks because you have to reach for guys knowing you wont pick again for 20 picks. I hate watching a guy i want slide for 10-15 picks and then he gets stolen because im at the end of the 20 pick run. mid-round is my favorite because with only 10 players gone between each pick, you can get a better idea who will be available with your next pick and you have a better chance of players falling to you for good value.