i may be way off here, but i think 2nd/3rd round is a little to high for at least me, i think late 3rd early 4th... i mean Knowshon still isn't even RB1 and most likely won't be to start the year as talks are both Buckhalter and Jordan are going to steal their fair share of touches from him... now i think he will make an impact, but certainly not right away, and i don't think he has a huge 1st year, and with 5 keepers your talking about knocking a vet that impacts a squad week in week out to take potential...
I think that is too early even in a larger keeper league like that. Say you are taking him in the 2nd/3rd round and the guy only starts even 8 games this year aren't you really setting yourself back for the 1st season then? Figure you are missing out on a true #2 RB or WR using that pick on a guy who "may" provide you large numbers later, just doesn't make sense to me. There's at least 3-4 rookie rb's who are going to make a big impact in the future why not wait a little bit and take a Greene or McCoy while getting yourself a solid #2 WR/RB with your 2nd/3rd rounder?