For what it's worth, this is my point of view.
I go safe picks over boom/bust all the time. Consistency is the top determining factor in my selection. Ala, westbrook. He consistently puts up top flight points and consistently misses ~3 games a year. I know what I'm getting. This strategy put me as the top average point scorer for my entire season last year. I consistently put up 8 more pts than the league average.
HOWEVER, I also had the toughest schedule. It was a league joke that anyone who played me had a monster week. Those boom/bust players always boomed on programatik Sunday. I've done this for 2 years now and it's pretty much turned out the same each time. Last year I did a little better than the year before. Chances are, I'll get boomed again by someone that gets hot during the playoffs. But from my standpoint, I'll have a better opportunity of my consistent guys getting me a championship than hoping that my guys boom at the right times.