Sounds like a crazy league! With the fact that you have to start 3 RB, that puts even more of a premium on RB's. It doesn't matter what your QB scoring is, I wouldn't touch a QB until round 5 - 8. I would try to grab 2 stud RBs with your first 2 picks and then grab a RB or WR in rounds 3, 4, and 5 depending on who is available in each round and where the better value is. I would try to leave round 5 with 3 RBs and 2 WRs. Depending on who is available in round 5, I would take the best player available at the RB, WR, or QB position. Grab RBs while everyone is grabbing a QB in the first few rounds! Target McNabb, Romo, Ryan, Schaub, Palmer, Hasselbeck, Cutler, etc later in the draft!