I would go with Moss, Welker,and then Brown and Rice. Both will get their fair share of touches and should catch a fair share of check downs and screen passes. Portis is tough to bench and I could see you playing him over Rice in a standard league, but in a PPR I like Rice's potential to catch 5-8 check down passes and screens. Portis will be lucky to catch 2 balls all night.
QB: Brees, Rodgers, E. Manning
RB: D. Mcf, Grant, L. Wash, R. Rice, D. Brown
WR: Megatron, Driver, Hester, Ginn, N. Washington
TE: Shiancoe, Fasano
12 teams, PPR league