Talent is talent, yes. But, match-ups are match-ups, too. I feel much better starting Thomas even with all NO's receivers. Colston MAY get a reception down field. Maybe. I think Brees is going to be going all over to move the ball and I watched last year when the other WO's caught great TD passes over my then Colston. Yeah, I know last year was last year and all that, but, you cannot discount Moore, Henderson, Meacham?, tight ends, etc. Just too many weapons for Brees.
I also have Knox and Marshall. I am starting Brandon. He is the primary and bigger target, no matter what the defense. Knox would be my other starter, but I have Smith(NYG). If I started MC I would be hoping for the ball, not expecting it. Good luck, though, if you start him.