I'm not crazy about either of your QBs but I would go with Ryan. I think it will be a high scoring game. As for flex, I would start Sproles. Good luck!
Help with mine pleaseviewtopic.php?f=19&t=458775
0.5 PPR 14-team league. All TDs are 6.
QB - Vick, Tannehill
RB - CJ2K, TRich, Pierre Thomas, Redman, lamar miller
WR - S Smith (CAR), Demaryius, Hartline, TY Hilton, Hixon
TE - Witten, Chandler