If he's the best option, I think you do it regardless if they are on the same team. It puts a lot into the SD basket, but hopefully for you, Boldin isn't out that long. They really need to let his ankle heal.
12 Team League. We start 2 QBs and get .5 PPR, otherwise standard scoring QBs: Stafford, Fitzpatrick, Collins RBs: Charles, Mendenhall, Best, Starks, Carter, Karim WRs: D. Jackson, Marshall, S. Smith, Green, TE: Hernandez, Cook