I'd probably go with Brady, too, but the Colts held the Texans high-powered defense to 17 last week. That game looked like it might be a shootout, but wasn't.
There are a lot of opinions expressed on the thread below about the same decision:viewtopic.php?t=460246
Hope that helps...
12 team, H2H, Standard Scoring (Starters in bold)
QB: P. Manning, Luck
WR: Julio Jones, Welker, Alexander, Hilton, Shorts
RB: Rice, Wilson, BJGE, LeShoure
DEF: DET, SD