At this point in the season, I say go for the best starting lineup you can. It's risky, but I would do it.
12 Team League. We start 2 QBs and get .5 PPR, otherwise standard scoring
QBs: Stafford, Fitzpatrick, Collins
RBs: Charles, Mendenhall, Best, Starks, Carter, Karim
WRs: D. Jackson, Marshall, S. Smith, Green,
TE: Hernandez, Cook