You don't sit your studs! You cannot bench Wayne just because of one bad week. The more reason to start him because you know he's gonna bounce back..
Though, I do like your alternate options. Holmes, Welker, and Meachem are good starts. But I would not bench Wayne. Calling Meachem Brees' number one is a stretch. Brees likes to spread it around and in terms of pecking order, Colston is still Brees' number one.. That Saints team has so many options.. a different receiver goes off every week. Meachem has been hot.. but I think he's due to come back down to Earth.. and this week might be it..
Wayne, Welker, and Holmes would be my picks.
QB - Drew Brees, Tony Romo
RB - Adrian Peterson, Trent Richardson, Alfred Morris, Jacquizz Rodgers
WR - Brandon Marshall, Julio Jones, Vincent Jackson, Anquan Boldin, Golden Tate
TE - Heath Miller
DEF - Rotating
K - Justin Tucker