I am not sure Best will be the main back yet. I would not take him over any WR1. The numbers receivers are putting up now matching RB totals. Team often have 2 WR's over 1000 yards. I might even take a good WR2 over Best.
Not to mention they are the Lions and will again always be playing from behind which mean throwing a lot and could mean a lot of Smith since he showed to be a decent receiver.
QB: BREES, Cutler
RB: TURNER, MCGAHEE, R. JENNINGS, Leshoure, D. Williams, Hillman, Hunter, Dwyer
WR: CRUZ, GARCON, Amendola, Edwards, D. Baldwin