I would disagree a bit in that you can predict sacks and you should use that to your advantage.
Those 20 point bonuses can be game changers. You want some of the guys capable of doing that.
To get down to names I would put Allen, Peppers, Williams, Tuck, Cole in an elite group at DL. After that it gets a little dicey and will be hit or miss.
Ware, Dumervil, Woodley, Harrison, C Matthews, Orakpo and Suggs I would target at LB. I'd take Willis or Beason in that group as well - but they should be long gone and I actually would prefer most of the others. In reality you need to watch which of these players are being drafted, then swoop in as late as you can and grab as many as you can.
With that scoring - at some point you also have to consider playing matchups with some of your D spots - so reaching for a few 'keepers' early and then picking over leftovers at D that can be cheaply churned isn't to be ignored.
Adding to my other response in the Draft forum, I guess I'd probably force myself to reach for some of those D players a round earlier than I normally would. Don't be first to draft D - but pay attention when people do. You can ignore 3-4 early D picks - but a run of 5-6 of those coveted players going off the board early means you need to start weighing the consequences of jumping in vs. filling holes on offense.
Before you really take any of this advice too seriously, what does the rest of your league scoring look like? Bonuses for long TD's or other strange scoring to offset these heavy D bonuses? If the offense is normal and the D is really skewed - then drafting D early and often becomes a viable strategy to anticipate.
What Would Purple Jesus Do?