Actually it was much easier to run on Carolina than pass on them last year so Williams would seem to be the better play based on last years trends. However, since this is a new season only time will tell, but I would probably play Williams as he is apparently the number 1 going against a Cleveland D.
QB's Brady, Alex Smith
RB's MJD, Jacobs, Addai, Reggie Bush
WR's Crabtree, Mike Wallace, Harvin, Garcon, V. Jackson, Knox