I like Mike Williams, but he's got a terrible matchup this week, and as he seems like the only threat through the air, I'd imagine Pittsburgh will key in on him. Demaryius Thomas has decent matchup, and he had a great game last week.. I think Thomas has great upside. Harvin, if he plays, has a great matchup, but if they go up, it might turn into an AP show. I'd like to see more then 1 week out of Murphy before I give him a go. Floyd is probably the safest bet.
I'd either go safe with Floyd if you think you are going to need points. If you want to go for upside, Thomas could have a huge game, as that could turn into a shootout depending on if Denver's offense can keep up. I'd like to say Harvin, but I haven't seen much from him in two weeks so far. Floyd for safety, Thomas for a possible huge game.