Thomas and Mathews.
As you said, Mathews is the healthiest, and has a favorable match-up against Arizona. Thomas, who did practice today, also has a favorable match-up against the horrid Panthers. Best has a horrible match-up against Green Bay, and all it will take is a little pain before the Lions give the ball to Morris and the presumably active Kevin Smith.
QB: Cutler, Freeman
WR: A. Johnson (Gaffney)
RB/WR/TE: Nicks (Boss)
RB/WR/TE: Tomlinson (Greene, Jennings, Davis)