I think that in the last few years, if you had a Peyton Manning and Tom Brady and could trade one, you could clean up. It doesn't matter if you appear desperate. People would make trades for those guys. THIS year? You're hosed. Sometimes it does work. I loaded up on WR talent... at one point I had Roddy White, Anquan Boldin, Maclin, Britt and Bowe. I wheeled and dealed to get the starting RB I was desperate for (because my #2 RB from draft day, DeAngelo Williams, basically never played this year!)
I play a little too gentleman-like. I screwed up on draft day and accidentally bid on the Pats D, by bumping the min bid. It meant that I paid $2. Not a big deal, but the problem was, it was a roster space that I couldn't afford. It was a technical error on my part... I had no intention of owning that D, or playing that D... purely an accident. But I decided that I wouldn't slow the league down by asking them to take it back. There were 2 other glitches that people caused on the draft, which were corrected by the commish shortly after my mistake. I damaged my team by not wanting to inconvenience people (I feel that if it's your fault, suck it up) and these other teams got problems corrected. So 2010 draft _I_ was the embarrassment.
I made up for it by losing game 1, and then winning 10 in a row. Hopefully I get the last laugh.