The defense is the easier decision... take NE against GB w/o Aaron Rodgers and absolutely NO running game all day long!
For your WR choices, it would help to know if your league was a PPR league or not, assuming that it isn't... I'd start Bowe and Moss. The other two choices have tough matchups this week.
I hope this helps! Please gimme a hand with my question, thanks! viewtopic.php?t=488321