I start to become a contrarian on Baldwin about early/mid 2nd. In non-PPR, his upside is a lot more appealing than the other WRs past Little. Even though I don't like his game, he has some Vincent Jackson in him, and could be that type of player. K makes a good point about Haley, and I think that's the biggest concern. There's already talk of a "tough love" approach towards Baldwin which, based on Haley's track record, I don't think will work.
I really liked Little when he was a possible 4th round pick in the NFL and 2nd round sleeper in fantasy. Now that he's the 3rd WR off the board and expected to contribute as a WR1 right off the bad, I think there's risk you have to acknowledge. He switched back and forth between RB and WR in college - which could be a plus for RAC stats - but alongside his 1 year suspension is a big negative to experience. Also, you can't knock Baldwin's attitude without admitting Little was both suspended and not honest during draft vetting about his part in being suspended. I'll take the risk in PPR, but without PPR, I'd much rather trade the pick.
If the question is who will have the best fantasy football production over a 4 year window, it could very well be Newton. I may not be sold on him as an NFL QB, but if you look at what Tebow did as far as fantasy production last year, it's easy to see Newton rack up stats for a few years while he tries to figure things out. One or two of the Vereens or Alex Greens or Powells or Hunters will be more valuable assets in a year or two but I think it's pretty impossible to say at this point which will hit.