Dealing with the snake pick in deeper leagues can be tough.
Does this league award any points per reception? If so, then I could see doing something like what you did in draft 2. Going WR/WR towards the end of the snake in PPR league is definitely a strategy that I would vouch for. However, if this is non-PPR I would likely open up RB/WR. You have no safe RBs in your second draft. Rookie running backs have a lot of upside but they are unproven commodities. I'd feel a lot better with someone a little more sure-fire.
PPR I'd shoot for 2 of Megatron, Roddy White, Larry Fitzgerald, Hakeem Nicks, and Mike Wallace.
If it is non-PPR I'd look to pair one of those wideouts with a falling RB like Rashard Mendenhall, Matt Forte, Darren McFadden, or even one of the older trio of Frank Gore, Michael Turner, Steven Jackson.
Good luck in 2011