Is this a PPR league? I'm assuming standard scoring but I figure I'd just make sure.
Having too many running backs is never a problem. You could possibly move one of Michael Turner, Ahmad Bradshaw, and Shonn Greene for an upgrade at either QB or WR. Don't rush to make a move however, as your roster is decently squared away. A couple weeks into the season your fellow owners will likely realize that starting WRs who catch 4 balls a game in their flex spot really drags down their total score. You should be able to get decent value for one of your backs. If Ochocinco doesn't pan out in New England and Mike Thomas doesn't break out like many have projected, you will be able to patch up your WRs. If Eli continues to be a low end QB1, you can upgrade there. If Michael Turner shows signs of slowing down early in the year, you can actually hold on to your backs and recover nicely from losing your second round pick. The options are seemingly endless
Good luck in 2011.