This is a solid team in a 12 team league, especially now that it seems like Jeremy Maclin should be good to go by the beginning of the season.
Maclin may start off a bit slow, but as long as he doesn't miss regular season time then I'd chalk that up as a win. Two great running backs in Arian Foster and Matt Forte should be able to anchor your team. They both benefit nicely from PPR. I am a bit worried about Michael Crabtree as your WR3. He is a talented player, but it hasn't shone through in the NFL just yet. Jim Harbaugh may be able to breath some life into that offense, but I'm just not high on the 49ers passing game. Through in to that mix the fact that Crabtree has missed significant time, and its just not a great situation. Both Simpson or Ford could break out and fill that slot though. JerMichael Finley has a very high upside, and he has a chance to put up numbers that will rival WR2s. Freeman and Stafford round out your offense nicely. At least one of them will finish as a top 10 QB.