I agree with Egg2828, despite his ridiculous name. In a 10 team PPR, you probably won't love the RB's that are still around at the end of the first round to have as your best players. I'd go WR/WR. Then, in the 3/4 turn think about targeting some of those underrated receiving RB's like Ahmad Bradshaw, Jahvid Best, Felix Jones, etc. I would expect two of those types of backs to be around there. Then, as Egg said, you can target a 2nd tier, underrated QB such as Romo, Roethlisberger, or Schaub at the 5/6 turn, along with another back or WR. Later, look for high upside receiving backs like a Reggie Bush.