It's already Week 3 and I STILL don't see the hype over Matthews in terms of Fantasy play. Best is easily the better start for this week, Tolbert is just a vulture for touchdown's. I'd say you're guaranteed atleast a TD and 50 yards for Best, which has been pretty standard for him.
10 team H2H league, standard scoring [NFL.com]
QB: A. Rogers
RB: MJD, S. Jax, J. Starks, D. Murray, M. Bush
WR: M. Wallace, B. Marshall, P. Harvin, M. Colston, L. Robinson
TE: O. Daniels, J. Gresham
K: Sebastian Janikowski