I think you go with Sproles and Murray. Even when Blount had the feature back role to start the season the Bucs were passing a lot and he was not utilized enough. The fact that Graham was used as the 3rd down back when Blount was healthy shows that they dont trust him in blitz pickup so even though he may be on the field more it may not equate to more touches.
Couple all that with a pissed off Saints team I see the Bucs passing a lot to try and keep up, probably wont be a good game for Blount.
10 Team Std Scoring No PPR
WR Julio Jones
WR Dez Bryant
K and Def by committee
Jordy Nelson, Ben Tate, David Nelson, Kendall Hunter, John Dwyer