I would roll with Eli and Holmes
I get that grossman has a good matchup, but, well, I live in chicago, and while not a bears fan, I have seen many games where he looked horrible in what was a "good matchup"
Eli is more talented with a better team around him
2012 Playoff Bound Teams
RB: McCoy, Mendy
WR: CJ, VJax, Stevie Johnson
RB: Rice, Grant
WR: Austin, Wallace, Welker