Ah, the question all Forte, Peterson and Charles owners are asking.
I think so.
If you look at Jamaal Charles 2010 finish, his performance was blinding. Played all 16 games, and was considered up there with A. Foster. He had I think 230 carries for around 1500 yards, and close to 50 receptions for around 450 yards. I think he only had 8 or 9 TD's, but he was close to Arian Fosters numbers with a significant amount of less carries. This preseason he had a game with 3 carries for 12 yards and 1 catch for 11 yards. This sample is small, but it still shows the A) he is a hybrid back and B) they are going to get the ball in his hands multiple ways.
The addition of Peyton Hillis and his torn ACL obviously work against him, but I am guessing Charles will still have the fire.
The ACL tear was in week 2 of last year which has given him plenty of recovery time. And while Hillis will be stealing carries and red zone situations, take solace in knowing he put up VERY decent numbers playing aside Thomas Jones.
Hope this helped you.