At RB I'd go with:
Donald Brown and Jennings.
Browns starting and while in a tough matchup will get carries as well as be involved in the passing game as a receiver out of the backfield. While the matchups tough, he's capable of breaking a big run, screen or getting GL work.
Jennings is starting and should get 15+ carries and has looked good. Minnesota isn't a scary matchup at all and I could see Jennings turning out a solid 75+ yds rushing and a TD.
At WR: Dez, Djax and Meachem.
Dez is your top drafted WR and with Witten out, a must play.
Djax had a decent preseason and should be back to his 2010 form. Haden can't cover him and Maclin,so I like his chance at a big play or 2 after Maclin establishes himself as a possession receiver and RZ threat.
I'm going Meachem solely off a Gut feeling.Wayne's a heady veteran WR and should get targets from luck, but the Chicago matchups not very inticing. Meachem is now a WR2 in San Diego and Rivers has to throw the ball to someone. Oaklands a decent matchup, I can see rivers finding Meachem downfield for a big play or 2.
Help me out with my TE situation for week 1?viewtopic.php?t=517620