In the first league I would go R. Griffin at QB, A. Hernandez at TE, and S. Ridley at RB2. The last decision (RB2) is the toughest, and I wouldn't blame you for going either way. If you don't have confidence in the NE running game, you should go with your gut and plug in A. Bradshaw.
In the second league I would definitely go with H. Nicks at WR2 and A. Bradshaw at flex. Nicks has shown that he can play through injury, so I don't believe his questionable status should be of huge concern. I believe both of those players have significantly more potential for fantasy production. At TE, I would definitely go with K. Rudolph. Witten needs to show that he is a reliable/unhindered part of that Dallas offense until you can start playing him.
Please help me with my trade if you have time: viewtopic.php?t=520260