If you have any way of knowing how leshoure is before game time, I would go leshoure. Arizona is not a strong running team. Thats not just dependent on who their back is. So my vote is leshoure.
10-team keeper league - QB, 2 RB, 2 WR, TE, FLEX, D/ST, K
QB - Newton, Palmer
RB - R. Matthews, Martin, Stewart, F. Jones, B. Brown
WR - Julio, Austin, Maclin, Heyward-Bey, Amendola, D. Alexander
TE - Graham
D/ST - Bears
K - Tynes