My gut says Spiller. (Also, I'm playing against Mathews this week. LOL)
Seriously though, you're better off with Spiller. He has proven more to this point than Mathews, and faces a
slightly softer run D.
In regards to the QB issue, I think you are right. Tannehill should have a nice game. Don't be surprised, however, if Cam ends up having a better one.
Good luck!!
Help me out pls,
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