Call this a gut feeling more than anything but I'd give the edge to Matt Ryan over Eli this week. I see Atlanta struggling to run the ball against the Giants so he'll be forced to throw, especially if the Giants jump ahead early. I'd expect the Giants to be running a more balanced attack. It doesn't necessarily mean Eli won't have a good line but I see Matt Ryan throwing for over 300 yards as a pretty safe assumption (and he'd still have Tony Gonzalez and Julio Jones in the passing game even if Roddy White isn't at 100%).
I agree with your assumption that the Lions are your safer defensive play. Arizona's QB play has been terrible and I don't think Ryan Lindley suddenly became competent in practice this week. I'd be shocked if Arizona's offense scored more than half the points GB puts up today against the Bears.
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