No disrespect to Clint, Deuce, or anyone else, as you really couldn't go wrong with any of the guys mentioned as a #1 overall, but in my 12 team league we get a point per catch, and that makes LT clearly the most valuable RB. He has been producing more as a receiver than as a RB the last few weeks.
As others have said, could you imagine what that team could be if they only had a "D?" Or a o-line. Remember that they have been riddled with injuries all year and he still has 1300+ yards on the ground.
I love Priest too, but as a younger back with the same yardage, you give the nod to youth.