10 - 2nd or 6th
12 - 2nd or 6th
Simply because enough people are high on LT you could get Priest at #2, if not you get LT, which is fine by me. The 6th is rather nice as well, b/c you get whoever out of Duece, ALexander, Portis, and Green that falls to you. With all the 2nd round RBs being very similar in risk/potential, I dont see any real downside to picking later in the 2nd round. Rudi, Barlow, Henry, D. Davis, etc they're all about the same to me.
in a 20 man league, I'd definitely want the 6th pick. Still getting one of those truly elite RBs, and a fairly good chance of a top 5 WR being around when you pick again (or possibly still a 12 team league's equivalent of a 2nd round RB).