I've thought about that (since I love Seattle's offense).
Theoretically, you could draft Shaun Alexander in Round 1, Darrell Jackson in Round 2, Matt Hasselbeck in Round 3, and Koren Robinson in Round 4.
I think most people would be pretty happy with that lineup on a week to week basis.
But like they've been saying, the problem would be that if the Seahawks happen to play the Ravens that week, there's a good chance you're going to lose. But if they happen to play Arizona, there's a good chance you're going to blow your opponent out of the water.
You could do the same thing with teh Saints'
Aaron Brooks, Deuce McAllister, Joe Horn, Donte Stallworth, Boo Williams.