I've gone, RB, RB, WR, WR, WR or RB, WR, RB, WR, WR.
Three solid WRs will be a big advantage over someone starting some crapshow as his 3rd. In one league I have Chad J, Santana Moss, and Price (Deuce and Domanick as RBs...Penny as QB). In another, I have Chad J, Steve Smith, and KRob (Ahman and Barlow as RBs...Bulger at QB).
What are you going to take 5th? a QB? TE? I'd rather fill the 2 RB and 3 WR spots, then go QB, then probably back to RB.