If you think they're passing, use Dime, Engage Eight - gets me a sack or INT 50% of the time. If you think they're running, use Nickel, Over Storm Brave. They don't stand a chance
I also like to use a 46 defense a lot, I guess beause it stops the run with it nearly all the time, and you can also stop the pass if you send a lot fo guys into zone defense. But you can get burned using it too.
HB slam works nicely for a first down run, and HB dive/inside usually has some holes open up, but not on the inside like they should - I can usually run off tackle for a good gain using dive/inside. And if you need 10 yards, use a hook route with your #2 WR, and it works pretty much every single time. It's good to use against the computer unless they have 2 really good CB's, but against a real person they'll catch on pretty quickly. And then there's the screen pass which works with pretty much every offense in Madden; usually good for 5 yards at least. It's a nice second down play, with your #1 WR on the fly, and if he's in single coverage, toss it up. If not, screen pass.
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