I have done this in the past. Moss and C.Carter. They worked out very well for me. The key is that one of the WRs have to be in the Top 10 IMO. In that instance, Moss was the stud and would always get a fair share of points but Carter was good enough to have big days without starving Moss. It also helps if the offense they're in is also Top 10.
Another ownder had the Rod Smith/McCaffrey combo and that worked out extremely well.
The combos I would consider starting right now:
Harrison/Wayne or Stokley
With the offenses they're in there is almost no reason to avoid one of these guys simply because you have the other.
Evil will always triumph because good is dumb.