I'd take Edgerrin before those guys. I'd take him over Ahman Green as well.
I'm not real concerned about Edgerrin. I think he is a steal at the end of the first round. After Ricky and LT, I think there are nothing but question marks. Portis had an excellent year last year but I'd want a little more history with my first rounder. Holmes is coming off an injury, and the team drafted LJ which may steal some TD's from him. Faulk is coming off a down season, and always seems to deal with knee issues. Alexander is up and down. A fantasy stud one month, in danger of being benched the next. Deuce has some injury history but may be the safest pick of the #3-7 RB's. Ahman Green has injury history and likely a reduced workload. Taylor and Lewis have injury issues, Tiki Barber may split carries (Levens may steal the goal line carries), Travis Henry isn't exactly a proven star, Corey Dillon has about 2 good games a year, Stephen Davis switches teams and loses his line, Curtis Martin is old, Eddie George is too and coming off injury plagued years (but I think another steal 3rd-4th round), William Green plays for the Browns and had a nice 2nd half but that is it. A-Train is slow and should be avoided except for a 3rd back or so.
I picked 9th of 10 and I took McNabb, then Edge with the 12th pick. McNabb was on pace to be the #1 fantasy player last year, and it wouldn't have been close if he didn't get injured. You need a RB leaving the first 2 rounds, but I think you are better off using one pick to get McNabb/Owens/Harrison. Getting 2 RB that are not in the top 6 or 7 will leave you at a disadvantage to every other team grabbing 2 RB's since one of their RB will be a top back. They will also get to pick again before you,. putting you in an even bigger hole. Grabbing McNabb/Owens and Edge would give you the RB with the biggest upside of those left (and highest trade value), and an elite QB or WR. You can still get a serviceable 2nd RB in the 3rd round (I took Eddie G - healed from foot ailments and came on after struggling for the first 5 games).
Pick the best available player in the 4th rounds and on, but a serviceable RB will be hard to find. If you took McNabb, I'd go WR in the 4th if a good one was left.
The meek ain't gonna inherit $#!%....'cuz I'll TAKE IT!